Pseudogenes used to be considered "junk" since they were parts of DNA strands, not whole strands. Now, researchers at The Scripps Research Institute (TSRI) have discovered that these pseudogenes can regulate cancer gene phosphatase and tensin homolog (PTEN) and control its activity.
PTEN is known as a "tumor suppressor" but in many cancers, PTEN is disabled. Researchers at TSRI are looking for ways to recharge PTEN. They are looking at how pseudogenes work and affect other genes in the body. This hopefully will lead to how to regulate PTEN in order to work in cancerous situations, which up until now has not been the case.
For the full article, visit http://www.aalatimes.com/2013/02/27/study-shows-how-pseudogenes-can-regulate-activity-of-cancer-genes/.
PTEN is known as a "tumor suppressor" but in many cancers, PTEN is disabled. Researchers at TSRI are looking for ways to recharge PTEN. They are looking at how pseudogenes work and affect other genes in the body. This hopefully will lead to how to regulate PTEN in order to work in cancerous situations, which up until now has not been the case.
For the full article, visit http://www.aalatimes.com/2013/02/27/study-shows-how-pseudogenes-can-regulate-activity-of-cancer-genes/.
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